Hormones & Longevity
Your hormones run everything.
Mood, energy, sleep, libido, weight — when they're off, you feel it.
Most doctors test one or two hormones and call it a day. But your hormones work as a system — estrogen, progesterone, testosterone, cortisol, and DHEA-S all influence each other. A single "normal" result can mask a bigger imbalance. This panel gives you the full picture.
Why this matters for women
A woman’s hormones influence far more than her menstrual cycle - they shape metabolism, brain function, cardiovascular health, muscle tone, sexual health, and long-term vitality. Hormonal shifts can begin years before menopause and may present as fatigue, weight changes, mood instability, sleep disruption, or reduced resilience to stress. By evaluating reproductive, adrenal, and growth-related hormones together, this panel helps identify imbalances that may affect fertility, perimenopause transition, metabolic health, and longevity. It supports more personalized strategies for optimizing energy, hormone rhythm, and healthy aging at every stage of life.
Symptoms to watch for
What we test
Cortisol, Total
Measures the body's primary stress hormone produced by the adrenal glands. Chronically elevated cortisol in women can lead to weight gain, bone loss, immune suppression, and menstrual disruption.
DHEA Sulfate, Immunoassay
Measures the adrenal hormone DHEA-S, a precursor to estrogen and testosterone. Elevated levels in women may signal PCOS or adrenal disorders; low levels are linked to fatigue and accelerated aging.
Estradiol, Ultrasensitive, LC/MS
Measures estradiol at very low levels using the most precise method. Essential for monitoring women in menopause, on anti-estrogen therapy, or evaluating subtle hormonal changes affecting fertility.
FSH
Measures follicle-stimulating hormone, which regulates ovarian function and egg development. Key for evaluating fertility, menopause status, and menstrual irregularities in women.
Igf 1, Lc/Ms
IGF-1 reflects the body's overall growth hormone activity and plays a key role in cellular repair, muscle and bone health, metabolism, and healthy aging.
Z Score (Male)
Provides an age- and sex-adjusted IGF-1 score that places results in context relative to a reference population. Helps assess whether IGF-1 levels in women are appropriate for their age and supports personalized evaluation of growth hormone activity.
LH
Measures luteinizing hormone, which triggers ovulation and supports early pregnancy. Essential for diagnosing PCOS, ovulation disorders, and perimenopause in women.
Progesterone, Lc/Ms
Measures progesterone, critical for regulating menstrual cycles and sustaining pregnancy. Low levels in women can cause irregular periods, difficulty conceiving, and increased miscarriage risk.
Prolactin
Measures prolactin, the hormone responsible for breast milk production. Elevated levels in non-pregnant women can cause missed periods, infertility, and may indicate a pituitary gland issue.
Sex Hormone Binding Globulin (SHBG)
Measures the protein that binds and transports sex hormones in the blood. Low SHBG in women is associated with PCOS, insulin resistance, and excess free testosterone causing acne and hair growth.
Testosterone Free (Dialysis)
Measures the unbound, active form of testosterone available to tissues. Helps identify hormonal imbalances contributing to acne, excess hair growth, hair thinning, or low sex drive in women.
Testosterone Total (MS)
Measures total testosterone using the gold-standard mass spectrometry method. Important for women because elevated levels may indicate PCOS, while low levels can cause fatigue, low libido, and muscle loss.
Who should consider this panel?
Women experiencing PMS, irregular periods, or painful cycles
Anyone in perimenopause or early menopause (ages 35-55)
Women on hormonal birth control who want a baseline
Postpartum women struggling with mood or energy
Anyone with unexplained fatigue, weight gain, or low libido
Cited sources
The Menopause Transition: Signs, Symptoms, and Management Options
Santoro N, et al.
Journal of Clinical Endocrinology & Metabolism, 2021.
DHEAS levels and mortality in disabled older women: the Women's Health and Aging Study I
Cappola AR, et al.
Journal of Gerontology: Series A, 2006.
Estrogen plus progestin and the risk of coronary heart disease
Manson JE, et al.
New England Journal of Medicine, 2003.
Women's Health Insights
Evidence-based articles to help you understand your body and take control of your health.
Signs Your Birth Control Is Affecting Your Hormones
Is your birth control affecting your hormones? Learn the signs that hormonal contraception may be impacting your mood, libido, energy, and overall health - and what lab tests can reveal.
Read Article: Signs Your Birth Control Is Affecting Your Hormones
