Autoimmune And Inflammation

80% of autoimmune patients are women.
If your body is attacking itself, these markers will show it.
Autoimmune diseases take an average of 4.5 years and 4 doctors to diagnose. This panel screens for the antibodies and inflammatory markers that reveal autoimmune activity — often years before a clinical diagnosis.
Symptoms to watch for
What we test
hs-CRP
Measures high-sensitivity C-reactive protein, a marker of vascular inflammation. Predicts cardiovascular events in women and is used alongside cholesterol to assess true heart disease risk.
Cyclic Citrullinated Peptide (CCP) Antibody (IgG)
Measures antibodies highly specific to rheumatoid arthritis. Critical for early diagnosis in women, who develop RA 2-3 times more often than men, allowing treatment before joint damage occurs.
DNA (ds) Antibody
Measures anti-double-stranded DNA antibodies specific to lupus. Levels often correlate with disease activity and kidney involvement, helping monitor lupus flares in women.
Sed Rate by Modified Westergren
Measures how quickly red blood cells settle, indicating inflammation. A general screening marker for women with suspected autoimmune flares, infections, or chronic inflammatory conditions.
ANA Screen,IFA, with Reflex to Titer and Pattern
Screens for antinuclear antibodies found in many autoimmune diseases. A critical first-step test for women with unexplained fatigue, joint pain, or rashes suggesting lupus, Sjögren's, or scleroderma.
Rheumatoid Factor
Measures antibodies commonly elevated in rheumatoid arthritis. Used alongside CCP antibodies for RA diagnosis in women, though it can also be positive in other autoimmune conditions.
Sm Antibody
Measures antibodies highly specific to systemic lupus (SLE). Important because lupus affects women 9 times more than men, and a positive result strongly supports a lupus diagnosis.
Sm/RNP Antibody
Measures antibodies associated with mixed connective tissue disease and lupus. Helps distinguish between autoimmune conditions in women, particularly when symptoms overlap between diseases.
TPO Antibody
Measures antibodies attacking thyroid peroxidase enzyme. The most common marker for Hashimoto's thyroiditis, an autoimmune thyroid disease that affects women 7 times more than men.
Who should consider this panel?
Women with unexplained chronic fatigue, joint pain, or brain fog
Anyone with a family history of autoimmune disease
Women with symptoms that multiple doctors can't explain
Those with a positive ANA who need more specific testing
Women experiencing hair loss, skin rashes, or dry eyes/mouth

Cited sources
The Prevalence of Autoimmune Disorders in Women: A Narrative Review
Angum F, et al.
Cureus, 2020.
Anti-CCP Antibody, a Marker for the Early Detection of Rheumatoid Arthritis
van Venrooij WJ, et al.
Annals of the New York Academy of Sciences, 2008.
Hashimoto's Thyroiditis: Epidemiology, Pathogenesis, Clinic and Therapy
Ragusa F, et al.
Best Practice & Research Clinical Endocrinology & Metabolism, 2019.
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